RTN3 Primary Antibody
Item Information
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Price
Description
RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
Product Overview
Entrez GenelD
10313
Aliases
HAP; ASYIP; NSPL2; NSPLII; RTN3-A1
Clone#
1E11
Host / Isotype
Mouse / IgG2a
Species Reactivity
Human
Immunogen
Purified recombinant fragment of RTN3 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
ICC (Immunocytochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Biochem Biophys Res Commun. 2005 Sep 9;334(4):1198-205.
2. Brain Res Mol Brain Res. 2005 Aug 18;138(2):236-43.
3. FASEB J. 2003 Jul;17(10):1238-47.
2. Brain Res Mol Brain Res. 2005 Aug 18;138(2):236-43.
3. FASEB J. 2003 Jul;17(10):1238-47.
Product Image
Immunofluorescence analysis
Figure 1: Confocal Immunofluorescence analysis of Hela (A), A431 (B) and THP-1 (C) cells using RTN3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
For Research Use Only. Not for use in diagnostic procedures.