RTN3 Primary Antibody
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Description
RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
Product Overview
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
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Immunohistochemical analysis
Figure 1: Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and breast cancer (right) using RTN3 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human Liver tissues using RTN3 mouse mAb
For Research Use Only. Not for use in diagnostic procedures.