RAB27A Primary Antibody
|Aliases||GS2; RAM; RAB27; HsT18676|
|Formulation||Purified antibody in PBS with 0.05% sodium azide.|
|Immunogen||Purified recombinant fragment of human RAB27A (AA: FULL(1-221)) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|IHC_P(Immunohistochemistry)||1/200 - 1/1000|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using RAB27A mAb against human RAB27A (AA: FULL(1-221)) recombinant protein. (Expected MW is 50.8 kDa)
Figure 2: Western blot analysis using RAB27A mAb against HEK293 (1) and RAB27A (AA: FULL(1-221))-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3: Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using RAB27A mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using RAB27A mouse mAb with DAB staining.
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
|References (references)||1. PLoS One. 2012;7(7):e41160.|
2. J Biol Chem. 2011 Feb 18;286(7):5375-82.