PTPRD Primary Antibody

Item Information

Catalog #

Size

Price

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.

Product Overview

Entrez GenelD

5789

Aliases

HPTP; PTPD; HPTPD; HPTPDELTA; RPTPDELTA

Clone#

5H5D7

Host / Isotype

Mouse / IgG1

Species Reactivity

Human

Immunogen

Purified recombinant fragment of human PTPRD (AA: extra 1077-1265) expressed in E. Coli.

Formulation

Purified antibody in PBS with 0.05% sodium azide

Storage

4°C; -20°C for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

FCM (Flow Cytometry)

1/200 - 1/400

ELISA

1/10000

References

1.Acta Paediatr. 2016 Mar;105(3):e132-41.2.Cancer Invest. 2012 Jun;30(5):422-32.

Product Image

Elisa

Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Figure 2:Western blot analysis using PTPRD mAb against human PTPRD (AA: extra 1077-1265) recombinant protein. (Expected MW is 47.4 kDa)

Figure 2:Western blot analysis using PTPRD mAb against human PTPRD (AA: extra 1077-1265) recombinant protein. (Expected MW is 47.4 kDa)

Western Blot

Figure 3:Western blot analysis using PTPRD mAb against HEK293 (1) and PTPRD (AA: extra 1077-1265)-hIgGFc transfected HEK293 (2) cell lysate.

Figure 3:Western blot analysis using PTPRD mAb against HEK293 (1) and PTPRD (AA: extra 1077-1265)-hIgGFc transfected HEK293 (2) cell lysate.

Flow cytometric

Figure 4:Flow cytometric analysis of HL-60 cells using PTPRD mouse mAb (green) and negative control (red).

Figure 4:Flow cytometric analysis of HL-60 cells using PTPRD mouse mAb (green) and negative control (red).

For Research Use Only. Not for use in diagnostic procedures.

Catalog#: 31467

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