PPP1A Primary Antibody

Item Information
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Price
Description

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product Overview
Entrez GenelD
5499
Aliases
PP-1A; PPP1A; MGC1674; MGC15877; PP1alpha; PPP1CA
Clone#
6D1
Host / Isotype
Mouse / IgG1
Species Reactivity
Human, Mouse
Immunogen
Purified recombinant fragment of human PPP1A expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. EMBO J. 2007 Mar 21;26(6):1511-21.
2. J Biol Chem. 2007 Jun 15;282(24):17806-15.
3. Mol Cell. 2007 Jul 20;27(2):262-74.
Product Image
Western Blot
Figure 1: Western blot analysis using PPP1A mouse mAb against Hela (1) and NIH/3T3 (2) cell lysate.
Figure 1: Western blot analysis using PPP1A mouse mAb against Hela (1) and NIH/3T3 (2) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.