PPP1A Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesPP-1A; PPP1A; MGC1674; MGC15877; PP1alpha; PPP1CA
ProductOrderP
Clone#6D1
Entrez GenelD5499
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human PPP1A expressed in E. Coli.
MW38kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Mouse
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
N
Catalog#: 20432
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Images
Western Blot
Figure 1: Western blot analysis using PPP1A mouse mAb against Hela (1) and NIH/3T3 (2) cell lysate.
Figure 1: Western blot analysis using PPP1A mouse mAb against Hela (1) and NIH/3T3 (2) cell lysate.
Product Overview
Description

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References (references)
References (references)1. EMBO J. 2007 Mar 21;26(6):1511-21.
2. J Biol Chem. 2007 Jun 15;282(24):17806-15.
3. Mol Cell. 2007 Jul 20;27(2):262-74.