PPARG Primary Antibody

Item Information

Catalog #

Size

Price

Description

PPARG: peroxisome proliferator-activated receptor gamma. This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Product Overview

Entrez GenelD

5468

Aliases

CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma; PPARG

Clone#

3A4A9

Host / Isotype

Mouse / IgG1

Species Reactivity

Human

Immunogen

Purified recombinant fragment of PPARG (aa170-270) expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Product Applications

WB (Western Blot)

1/500 - 1/2000

ELISA

1/10000

References

1. Sarcoidosis Vasc Diffuse Lung Dis. 2006 Jun;23(2):93-100
2. Hum Biol. 2007 Feb;79(1):111-9.
3. Hum Genet. 2008 Feb;123(1):35-40. Epub 2007 Nov 13.

Product Image

Western Blot

Figure 1: Western blot analysis using PPARG mouse mAb against truncated PPARG-His recombinant protein (1) and full-length PPARG(aa1-477) transfected CHO-K1 cell lysate (2).

For Research Use Only. Not for use in diagnostic procedures.