PON1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesESA; PON; MVCD5
ProductOrderP
Clone#4G8D3
Entrez GenelD5444
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human PON1 (AA: 20-155) expressed in E. Coli.
MW39.7kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
20-155
Catalog#: 30572
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Images
Western Blot
Figure 1: Western blot analysis using PON1 mAb against human PON1 recombinant protein. (Expected MW is 40.6 kDa)
Figure 1: Western blot analysis using PON1 mAb against human PON1 recombinant protein. (Expected MW is 40.6 kDa)
Western Blot
Figure 2: Western blot analysis using PON1 mAb against HEK293 (1) and PON1 (AA: 20-155)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using PON1 mAb against HEK293 (1) and PON1 (AA: 20-155)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 3: Western blot analysis using PON1 mouse mAb against human plasma cell lysate.
Figure 3: Western blot analysis using PON1 mouse mAb against human plasma cell lysate.
Immunofluorescence analysis
Figure 4: Immunofluorescence analysis of Hela cells using PON1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Figure 4: Immunofluorescence analysis of Hela cells using PON1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Immunohistochemical analysis
Figure 5: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using PON1 mouse mAb with DAB staining.
Figure 5: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using PON1 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 6: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using PON1 mouse mAb with DAB staining.
Figure 6: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using PON1 mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
DescriptionThe enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
References (references)
References (references)1. Redox Rep. 2012;17(5):214-8.
2. Cancer Epidemiol. 2012 Apr;36(2):e101-3.