PODXL Primary Antibody
|Aliases||PC; PCLP; Gp200; PCLP-1; MGC138240|
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Immunogen||Purified recombinant fragment of human PODXL expressed in E. Coli. |
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|IHC_P(Immunohistochemistry)||1/200 - 1/1000|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using PODXL mAb against human PODXL (AA: 109-324) recombinant protein. (Expected MW is 47.3 kDa)
Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer tissues (left) and kidney tissues (right) using PODXL mouse mAb with DAB staining.
Figure 3: Flow cytometric analysis of Hela cells using PODXL mouse mAb (green) and negative control (purple).
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. (provided by RefSeq)Tissue specificity: Glomerular epithelium cell (podocyte)
|References (references)||1. Blood. 2009 Jan 22;113(4):816-26. |
2. Am J Physiol Cell Physiol. 2009 Mar;296(3):C505-13.