PLA2G7 Primary Antibody

Item Information
Catalog # Size/Concentration Price
31819 100ug $341.00
Specification
AliasesPAFAD; PAFAH; LP-PLA2; LDL-PLA2
Clone#3E1G5
Entrez GeneID7941
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG1
ImmunogenPurified recombinant fragment of human PLA2G7 (AA: 22-441) expressed in E. Coli.
MW50kDa
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
IHC_P (Immunohistochemistry) 1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
22-441
Catalog
31819
$341.00
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Images

Elisa

Cell Culture Products

Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Cell Culture Products

Figure 2:Western blot analysis using PLA2G7 mAb against human PLA2G7 (AA: 22-441) recombinant protein. (Expected MW is 74.6 kDa)

Western Blot

Cell Culture Products

Figure 3:Western blot analysis using PLA2G7 mAb against HEK293 (1) and PLA2G7 (AA: 22-441)-hIgGFc transfected HEK293 (2) cell lysate.

Immunofluorescence analysis

Cell Culture Products

Figure 4:Immunofluorescence analysis of Hela cells using PLA2G7 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Immunohistochemical Analysis

Cell Culture Products

Figure 5:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using PLA2G7 mouse mAb with DAB staining.

Immunohistochemical Analysis

Cell Culture Products

Figure 6:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using PLA2G7 mouse mAb with DAB staining.

Product Overview
Description

The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.

References (references)
References (references) 1.J Thromb Thrombolysis. 2018 Jul;46(1):125-130. 2.Diabetologia. 2018 May;61(5):1155-1166.

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