PIDD1 Primary Antibody

Item Information
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Price
Description

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

Product Overview
Entrez GenelD
55367
Aliases
LRDD; PIDD
Clone#
3C5G8
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human PIDD1 (AA: 776-910) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1.Tumour Biol. 2016 Aug;37(8):10447-57.
2.Br J Cancer. 2007 May 7;96(9):1425-32.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using PIDD1 mAb against human PIDD1 (AA: 776-910) recombinant protein. (Expected MW is 40.8 kDa)
Figure 2:Western blot analysis using PIDD1 mAb against human PIDD1 (AA: 776-910) recombinant protein. (Expected MW is 40.8 kDa)
Western Blot
Figure 3:Western blot analysis using PIDD1 mAb against HEK293 (1) and PIDD1 (AA: 776-910)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3:Western blot analysis using PIDD1 mAb against HEK293 (1) and PIDD1 (AA: 776-910)-hIgGFc transfected HEK293 (2) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.