PGR Primary Antibody
Item Information
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Size
Price
Description
PGR: progesterone receptor. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined.
Product Overview
Entrez GenelD
5241
Aliases
PR; NR3C3; PGR
Clone#
8A11H1
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of PGR (aa730-871) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Cancer Sci. 2006 Dec;97(12):1308.
2. Mol Endocrinol. 2006 Nov;20(11):2656-70.
3. Mol Endocrinol. 2007 Jan;21(1):106-25.
4. J Clin Endocrinol Metab. 2007 Nov;92(11):4459-66.
2. Mol Endocrinol. 2006 Nov;20(11):2656-70.
3. Mol Endocrinol. 2007 Jan;21(1):106-25.
4. J Clin Endocrinol Metab. 2007 Nov;92(11):4459-66.
Product Image
Western Blot
Figure 1: Western blot analysis using PGR mouse mAb against truncated MBP-PGR recombinant protein (1) and truncated Trx-PGR(aa730-871) recombinant protein (2).
For Research Use Only. Not for use in diagnostic procedures.