PDGFA

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesPDGF1; PDGF-A
Clone#4C1F4
Entrez GenelD5154
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG1
ImmunogenPurified recombinant fragment of human PDGFA (AA: 87-211) expressed in E. Coli.
MW24KDa
Species ReactivityHuman, Mouse
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
Sequence
87-211
Catalog#: 32429
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Images
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Immunofluorescence analysis
Figure 2:Flow cytometric analysis of Hela cells using PDGFA mouse mAb (green) and negative control (red).
Figure 2:Flow cytometric analysis of Hela cells using PDGFA mouse mAb (green) and negative control (red).
Immunofluorescence analysis
Figure 3:Flow cytometric analysis of NIH/3T3 cells using PDGFA mouse mAb (green) and negative control (red).
Figure 3:Flow cytometric analysis of NIH/3T3 cells using PDGFA mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 4:Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using PDGFA mouse mAb with DAB staining.
Figure 4:Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using PDGFA mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 5:Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using PDGFA mouse mAb with DAB staining.
Figure 5:Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using PDGFA mouse mAb with DAB staining.
Product Overview
Description

This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants.

References (references)
References (references)1.Commun Biol. 2022 Mar 3;5(1):197.
2.Medicine (Baltimore). 2021 May 21;100(20):e25932.