PBEF1 Primary Antibody

Item Information

Catalog #

Size

Price

Description

PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

Product Overview

Entrez GenelD

10135

Aliases

VF; PBEF; PBEF1; VISFATIN; NAMPT

Clone#

1D3A12

Host / Isotype

Mouse / IgG1

Species Reactivity

Human

Immunogen

Purified recombinant fragment of PBEF1 (aa338-479) expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

4°C; -20°C for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

ELISA

1/10000

References

1. Mol Cell Biol. 1994 Feb;14(2):1431-7.
2. Eur J Immunol. 2002 Nov;32(11):3225-34.

Product Image

Western Blot

Figure 1: Western blot analysis using PBEF1 mouse mAb against truncated PBEF1-His recombinant protein (1) and full-length GFP-PBEF1(aa1-491) transfected COS7 cell lysate (2).

For Research Use Only. Not for use in diagnostic procedures.