PARP Primary Antibody
Item Information
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Size
Price
Description
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Product Overview
Entrez GenelD
142
Aliases
PARP; PPOL; ADPRT; ADPRT1; PARP-1; pADPRT-1; PARP1
Clone#
7A10
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Synthetic peptide of human PARP, conjugated to KLH.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1. Cytogenet Cell Genet. 1992;61(3):172-4.
2. J Immunol. 1997 Dec 1;159(11):5246-52.
3. J Biol Chem. 2001 Dec 7;276(49):45588-97.
2. J Immunol. 1997 Dec 1;159(11):5246-52.
3. J Biol Chem. 2001 Dec 7;276(49):45588-97.
Product Image
Western Blot
Figure 1: Western blot analysis using PARP mouse mAb against Jurkat (1), K562 (2), Hela (3), Raji (4),THP-1 (5) and SW620 (6) cell lysate.
Flow cytometric
Figure 2: Flow cytometric analysis of Jurkat cells using anti-PARP mAb (green) and negative control (purple).
For Research Use Only. Not for use in diagnostic procedures.