p63a Primary Antibody
Item Information
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Size
Price
Description
The p63 gene is a homologue of the p53 tumor suppressor gene. Like p53, p63 contains a transactivation (TA) domain induce the transcription of target genes, a DNA binding domain, and an oligomerization domain (OD), used to form tetramers. In contrast to p53, the p63 gene encodes for at least six major isotypes. Three isotypes (TAp63a, TAp63
Product Overview
Entrez GenelD
8626
Aliases
P51B; KET; p63α
Clone#
4E5
Host / Isotype
Mouse / IgG1
Species Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Synthesized peptide of human p63α.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Cancer Res. 2008 Jul 1;68(13):5122-31.
2. Eur J Med Genet. 2008 Sep-Oct;51(5):497-500.
2. Eur J Med Genet. 2008 Sep-Oct;51(5):497-500.
Product Image
Western Blot
Figure 1: Western blot analysis using p63? mouse mAb against A431 (1), Hela (2), Jurkat (3), THP-1 (4), NIH/3T3 (5), Cos7 (6) and PC-12 (7) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer (left) and lung cancer (right) using p63? mouse mAb with DAB staining.
Elisa
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
For Research Use Only. Not for use in diagnostic procedures.