P2RY2 Primary Antibody
Item Information
Catalog #
Size
Price
Description
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.
Product Overview
Entrez GenelD
5029
Aliases
P2U; HP2U; P2U1; P2UR; P2Y2; P2RU1; P2Y2R
Clone#
4F11E7
Host / Isotype
Mouse / IgG2b
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human P2RY2 (AA: extra mix) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Breast Cancer Res. 2014 Aug 26;16(5):R77.2.Carcinogenesis. 2014 Jun;35(6):1238-47.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using P2RY2 mAb against human P2RY2 (AA: extra mix) recombinant protein. (Expected MW is 10 kDa)
Western Blot
Figure 3:Western blot analysis using P2RY2 mAb against HEK293 (1) and P2RY2 (AA: extra mix)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of Hela cells using P2RY2 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.