OX40 Primary Antibody
Item Information
Catalog #
Size
Price
Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Product Overview
Entrez GenelD
7293
Aliases
TNFRSF4; ACT35; CD134; IMD16; TXGP1L
Clone#
2D1B8
Host / Isotype
Mouse / IgG2b
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human OX40 (AA: extra 29-214) expressed in HEK293 cells.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Oncotarget. 2015 Nov 10;6(35):37588-99.
2.Hepatology. 2014 Nov;60(5):1494-507.
2.Hepatology. 2014 Nov;60(5):1494-507.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using OX40 mAb against human OX40 (AA: extra 29-214) recombinant protein. (Expected MW is 50 kDa)
Flow cytometric
Figure 3:Flow cytometric analysis of Hela cells using OX40 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.