NTRK3 Primary Antibody
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Description
NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Product Overview
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Image
Western Blot
Figure 1: Western blot analysis using NTRK3 mouse mAb against extracellular domain of human NTRK3 (aa32-429).
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human lymph node using NTRK3 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.