NTRK2 Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
Product Overview
Entrez GenelD
4915
Aliases
TRKB; trk-B; GP145-TrkB
Clone#
10B6C4
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human NTRK2 (AA: 207-339) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1.Br J Cancer. 2014 Jun 10;110(12):2923-34.
2.Cancer Med. 2014 Feb;3(1):25-35.
2.Cancer Med. 2014 Feb;3(1):25-35.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western Blot
Figure 2:Western blot analysis using NTRK2 mAb against human NTRK2 (AA: 207-339) recombinant protein. (Expected MW is 40.6 kDa)
Western Blot
Figure 3:Western blot analysis using NTRK2 mAb against HEK293 (1) and NTRK2 (AA: 207-339)-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemical analysis
Figure 4:Immunohistochemical analysis of paraffin-embedded breast cancer tissues using NTRK2 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.