NTRK2 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesTRKB; trk-B; GP145-TrkB
ProductOrderN
Clone#8D2E8
Entrez GenelD4915
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human NTRK2 (AA: 207-339) expressed in E. Coli.
MW92kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
207-339
Catalog#: 30882
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Images
Elisa
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western Blot
Figure 2:Western blot analysis using NTRK2 mAb against human NTRK2 (AA: 207-339) recombinant protein. (Expected MW is 40.6 kDa)
Figure 2:Western blot analysis using NTRK2 mAb against human NTRK2 (AA: 207-339) recombinant protein. (Expected MW is 40.6 kDa)
Western Blot
Figure 3:Western blot analysis using NTRK2 mAb against HEK293 (1) and NTRK2 (AA: 207-339)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3:Western blot analysis using NTRK2 mAb against HEK293 (1) and NTRK2 (AA: 207-339)-hIgGFc transfected HEK293 (2) cell lysate.
Product Overview
DescriptionThis gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
References (references)
References (references)1.Br J Cancer. 2014 Jun 10;110(12):2923-34.
2.Cancer Med. 2014 Feb;3(1):25-35.