NR2C2 Primary Antibody

Item Information
Catalog #
Size
Price
Description

This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]

Product Overview
Entrez GenelD
7182
Aliases
TR4; TAK1
Clone#
8H11D4
Host / Isotype
Mouse / IgG1
Immunogen
Mouse IgG1
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Lung Cancer. 2015 Sep;89(3):320-8.
2.Oncotarget. 2015 Jun 20;6(17):15397-409.
For Research Use Only. Not for use in diagnostic procedures.