NFKBIB Primary Antibody
Item Information
Catalog #
Size
Price
Description
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.
Product Overview
Entrez GenelD
4793
Aliases
IKBB; TRIP9; NFKBIB
Clone#
7B4
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human NFKBIB expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Mol Cell Biol. 2004 Apr;24(7):3048-56.
2. J Biol Chem. 2004 Oct 15;279(42):44030-8.
3. J Bone Miner Res. 2009 Dec;24(12):2039-49.
2. J Biol Chem. 2004 Oct 15;279(42):44030-8.
3. J Bone Miner Res. 2009 Dec;24(12):2039-49.
Product Image
Western Blot
Figure 1: Western blot analysis using NFKBIB mouse mAb against Jurkat (1) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.