NFKB2 Primary Antibody
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
2.Mol Cancer Ther. 2013 Aug;12(8):1629-37.
![Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31639ea.jpg?v=1666704193)
![Figure 2:Western blot analysis using NFKB2 mAb against human NFKB2 (AA: 712-900) recombinant protein. (Expected MW is 45.9 kDa)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31639rwb.jpg?v=1666704193)
![Figure 3:Western blot analysis using NFKB2 mAb against HEK293 (1) and NFKB2 (AA: 712-900)-hIgGFc transfected HEK293 (2) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31639twb.jpg?v=1666704193)
![Figure 4:Western blot analysis using NFKB2 mouse mAb against NIH/3T3 (1), MCF-7 (2), and THP-1 (3) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31639lwb.jpg?v=1666704193)