NFE2L2 Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Overview
Entrez GenelD
4780
Aliases
NRF2
Clone#
1A6G6
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human NFE2L2 (AA: 356-589) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. J Exp Clin Cancer Res. 2012 Aug 19;31:66.
2. Physiol Genomics. 2012 Aug 1;44(15):754-63.
2. Physiol Genomics. 2012 Aug 1;44(15):754-63.
Product Image
Western Blot
Figure 1: Western blot analysis using NFE2L2 mAb against human NFE2L2 (AA: 356-589) recombinant protein. (Expected MW is 52.1 kDa)
Western Blot
Figure 2: Western blot analysis using NFE2L2 mAb against HEK293 (1) and NFE2L2 (AA: 356-589)-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using NFE2L2 mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.