NFE2L2 Primary Antibody
|Formulation||Purified antibody in PBS with 0.05% sodium azide.|
|Immunogen||Purified recombinant fragment of human NFE2L2 (AA: 356-589) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|IHC_P(Immunohistochemistry)||1/200 - 1/1000|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using NFE2L2 mAb against human NFE2L2 (AA: 356-589) recombinant protein. (Expected MW is 52.1 kDa)
Figure 2: Western blot analysis using NFE2L2 mAb against HEK293 (1) and NFE2L2 (AA: 356-589)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3: Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using NFE2L2 mouse mAb with DAB staining.
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
|Description||This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene. |
|References (references)||1. J Exp Clin Cancer Res. 2012 Aug 19;31:66. |
2. Physiol Genomics. 2012 Aug 1;44(15):754-63.