Neuropilin-1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesNRP1; NP1; NRP; BDCA4; CD304; VEGF165R
ProductOrderN
Clone#5B1E11
Entrez GenelD8829
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenSynthesized peptide of human Neuropilin-1 (AA: 45-59).
MW103.1kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
45-59
Catalog#: 30824
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Images
Elisa
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Flow cytometric
Figure 2:Flow cytometric analysis of Hela cells using Neuropilin-1 mouse mAb (green) and negative control (red).
Figure 2:Flow cytometric analysis of Hela cells using Neuropilin-1 mouse mAb (green) and negative control (red).
Western Blot
Figure 3:Western blot analysis using Neuropilin-1 mouse mAb against Jurkat (1), Hela (2), and HUVEC (3) cell lysate.
Figure 3:Western blot analysis using Neuropilin-1 mouse mAb against Jurkat (1), Hela (2), and HUVEC (3) cell lysate.
Product Overview
DescriptionThis gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
References (references)
References (references)1.Leuk Res. 2012 Feb;36(2):169-73.
2.Blood. 2011 Jan 20;117(3):920-7.
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