NCOR1 Primary Antibody
Item Information
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Price
Description
NCOR1: Nuclear receptor co-repressor 1. This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.
Product Overview
Entrez GenelD
9611
Aliases
N-CoR; TRAC1; hN-CoR
Clone#
7A7A9
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of NCOR1 (aa1-192) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Mol Cell Biol. 2005 Aug;25(15):6404-14.
2. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1471-80.
2. Biochem Biophys Res Commun. 2006 Jul 14;345(4):1471-80.
Product Image
Western Blot
Figure 1: Western blot analysis using NCOR1 mouse mAb against truncated Trx-NCOR1 recombinant protein (1).
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human cerebra (left) and breast carcinoma tissue (right), showing nuclear location with DAB staining using NCOR1 mouse mAb.
For Research Use Only. Not for use in diagnostic procedures.