Myoglobin Primary Antibody
Myoglobin (MB), with 154-amino acid protein (about 17kDa), is a member of the globin superfamily and expression of myoglobin is highest in skeletal and cardiac muscle. Functionally, myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia. Myoglobin is also thought to buffer intracellular O2 concentration when muscle activity increases and to facilitate intracellular O2 diffusion by providing a parallel path that augments simple diffusion of dissolved O2. Furthermore, myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.
Purified antibody in PBS containing 0.03% sodium azide.
4°C; -20°C for long term storage
Figure 1: Western blot analysis using Myoglobin mouse mAb against truncated Myoglobin recombinant protein(AA: 2-154).
Figure 2: Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue showing cytoplasmic localization using anti-Myoglobin antibody with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.