MYL2 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesMLC2; CMH10; DKFZp779C0562
ProductOrderM
Clone#7C9
Entrez GenelD4633
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of MYL2 expressed in E. Coli.
MW19kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
2-166
Catalog#: 20324
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Images
Western Blot
Figure 1: Western blot analysis using MYL3 (1) and MYL2 (2) mouse mAb against rat fetal heart tissue lysate.
Figure 1: Western blot analysis using MYL3 (1) and MYL2 (2) mouse mAb against rat fetal heart tissue lysate.
Product Overview
Description

MYL2(myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

References (references)
References (references)1. DNA Seq. 2003 Oct;14(5):339-50.
2. Oncogene. 2002 Aug 29;21(38):5852-60.