MYL2 Primary Antibody
Item Information
Catalog #
Size
Price
Description
MYL2(myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
Product Overview
Entrez GenelD
4633
Aliases
MLC2; CMH10; DKFZp779C0562
Clone#
7C9
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of MYL2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. DNA Seq. 2003 Oct;14(5):339-50.
2. Oncogene. 2002 Aug 29;21(38):5852-60.
2. Oncogene. 2002 Aug 29;21(38):5852-60.
Product Image
Western Blot
Figure 1: Western blot analysis using MYL3 (1) and MYL2 (2) mouse mAb against rat fetal heart tissue lysate.
For Research Use Only. Not for use in diagnostic procedures.