Myeloperoxidase Primary Antibody

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Description

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.

Product Overview
Entrez GenelD
4353
Aliases
MPO;myeloperoxidase
Clone#
9B12G7
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of MPO (aa1-193) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. J Pediatr Hematol Oncol. 2007 May;29(5):293-7.
2. PLoS ONE. 2008 Jun 30;3(7):e2816.
Product Image
Western Blot
Figure 1: Western blot analysis using MPO mouse mAb against truncated Trx-MPO recombinant protein (1),truncated MBP-MPO (aa1-193) recombinant protein (2) and truncated MPO(aa165-745)-hIgGFc transfected CHO-K1 cell lysate(3).
Figure 1: Western blot analysis using MPO mouse mAb against truncated Trx-MPO recombinant protein (1),truncated MBP-MPO (aa1-193) recombinant protein (2) and truncated MPO(aa165-745)-hIgGFc transfected CHO-K1 cell lysate(3).
For Research Use Only. Not for use in diagnostic procedures.