MYC Primary Antibody

Item Information
Catalog #
Size
Price
Description

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. (provided by RefSeq).

Product Overview
Entrez GenelD
4609
Aliases
MRTL; c-Myc; bHLHe39
Clone#
7E10
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human MYC expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Mol Cell. 2009 Sep 11;35(5):610-25.
2. Clin Immunol. 2009 Dec;133(3):324-32.
Product Image
Western Blot
Figure 1: Western blot analysis using MYC mAb against human MYC (AA:214-387) recombinant protein. (Expected MW is 44.7 kDa)
Figure 1: Western blot analysis using MYC mAb against human MYC (AA:214-387) recombinant protein. (Expected MW is 44.7 kDa)
Elisa
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
For Research Use Only. Not for use in diagnostic procedures.