MYC Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesMRTL; c-Myc; bHLHe39
ProductOrderM
Clone#7E10
Entrez GenelD4609
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human MYC expressed in E. Coli.
MW49kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
214-387
Catalog#: 30209
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Images
Western Blot
Figure 1: Western blot analysis using MYC mAb against human MYC (AA:214-387) recombinant protein. (Expected MW is 44.7 kDa)
Figure 1: Western blot analysis using MYC mAb against human MYC (AA:214-387) recombinant protein. (Expected MW is 44.7 kDa)
Elisa
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Product Overview
Description

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. (provided by RefSeq).

References (references)
References (references)1. Mol Cell. 2009 Sep 11;35(5):610-25.
2. Clin Immunol. 2009 Dec;133(3):324-32.