MYC Primary Antibody
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. (provided by RefSeq).
2. Clin Immunol. 2009 Dec;133(3):324-32.
![Figure 1: Western blot analysis using MYC mAb against human MYC (AA:214-387) recombinant protein. (Expected MW is 44.7 kDa)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/30209rwb.jpg?v=1666699372)
![Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/30209ea.jpg?v=1666699372)