MuRF1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesTRIM63; IRF; SMRZ; MURF2; RNF28
ProductOrderM
Clone#6H6D4
Entrez GenelD84676
FormulationPurified antibody in PBS with 0.05% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenSynthesized peptide of human MuRF1 (AA: 293-304).
MW40.2kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
Sequence
293-304
Catalog#: 30706
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Images
Immunohistochemical analysis
Figure 1: Immunohistochemical analysis of paraffin-embedded muscle tissues using MuRF1 mouse mAb with DAB staining.
Figure 1: Immunohistochemical analysis of paraffin-embedded muscle tissues using MuRF1 mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.

References (references)
References (references)1. Liver Int. 2013 May;33(5):714-21. doi: 10.1111/liv.12128. Epub 2013 Feb 24.
2. Cell Biochem Biophys. 2011 Jun;60(1-2):113-8.