MRP3
Item Information
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Size
Price
Description
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Product Overview
Entrez GenelD
8714
Aliases
MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757
Clone#
5F9B12
Host / Isotype
Mouse / Mouse IgG1
Species Reactivity
Human, Mouse, Rat
Immunogen
Purified recombinant fragment of human MRP3 (AA: 830-949) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4℃; -20℃ for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Adv Biol Regul. 2019 Aug;73:100634.
2.Mol Genet Genomic Med. 2020 Jun;8(6):e1124.
2.Mol Genet Genomic Med. 2020 Jun;8(6):e1124.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using MRP3 mAb against human MRP3 (AA: 830-949) recombinant protein. (Expected MW is 29.6 kDa)
Western Blot
Figure 3:Western blot analysis using MRP3 mAb against HEK293-6e (1) and MRP3 (AA: 830-949)-hIgGFc transfected HEK293-6e (2) cell lysate.
Immunofluorescence analysis
Figure 4:Flow cytometric analysis of HepG2 cells using MRP3 mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 5:Immunohistochemical analysis of paraffin-embedded lung cancer tissues using MRP3 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 6:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using MRP3 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 7:Immunohistochemical analysis of paraffin-embedded colon cancer tissues using MRP3 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 8:Immunohistochemical analysis of paraffin-embedded breast cancer tissues using MRP3 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 9:Immunohistochemical analysis of paraffin-embedded mouse colon tissues using MRP3 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 10:Immunohistochemical analysis of paraffin-embedded mouse spleen tissues using MRP3 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 11:Immunohistochemical analysis of paraffin-embedded rat kidney tissues using MRP3 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 12:Immunohistochemical analysis of paraffin-embedded rat spleen tissues using MRP3 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 13:Immunohistochemical analysis of paraffin-embedded rabbit rectum tissues using MRP3 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.