MPS1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesRPS27
ProductOrderM
Clone#7E3
Entrez GenelD6232
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of MPS1 expressed in E. Coli.
MW9.5kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
Sequence
N
Catalog#: 20352
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Images
Immunofluorescence analysis
Figure 1: Confocal Immunofluorescence analysis of Hela cells (A), BCBL-1 cells (B) and L1210 cells (C) using MPS1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
Figure 1: Confocal Immunofluorescence analysis of Hela cells (A), BCBL-1 cells (B) and L1210 cells (C) using MPS1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
Product Overview
Description

MPS1, also known as RPS27. It is a ribosomal protein. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. MPS1 is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

References (references)
References (references)1. Biochem Cell Biol. 1995 Nov-Dec;73(11-12):933-47.
2. Mol Biol Cell. 2003 Apr;14(4):1638-51.
3. Cell. 2008 Jan 25;132(2):233-46.