MPS1 Primary Antibody

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Description

MPS1, also known as RPS27. It is a ribosomal protein. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. MPS1 is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Product Overview
Entrez GenelD
6232
Aliases
RPS27
Clone#
4A12
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of MPS1 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Biochem Cell Biol. 1995 Nov-Dec;73(11-12):933-47.
2. Mol Biol Cell. 2003 Apr;14(4):1638-51.
3. Cell. 2008 Jan 25;132(2):233-46.
Product Image
Immunohistochemical analysis
Figure 1: Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and human brain (right) tissues using MPS1 mouse mAb with DAB staining.
Figure 1: Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and human brain (right) tissues using MPS1 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.