Mouse TUG Primary Antibody
Item Information
Catalog #
Size
Price
Description
The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.
Product Overview
Entrez GenelD
79058
Aliases
ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9
Clone#
4A11A6G11
Species Reactivity
Mouse
Immunogen
Purified recombinant fragment of TUG expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Nature 2003,425:727 - 733.
Product Image
Western Blot
Figure 1: Western blot analysis using TUG mouse mAb against NIH/3T3 cell lysate.
For Research Use Only. Not for use in diagnostic procedures.