MMP3 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesSL-1; STMY; STR1; CHDS6; MMP-3; STMY1
ProductOrderM
Clone#4F10
Entrez GenelD4314
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human MMP3 expressed in E. Coli.
MW54kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
189-441
Catalog#: 30311
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Images
Western Blot
Figure 1: Western blot analysis using MMP3 mAb against human MMP3 (AA: 189-441) recombinant protein. (Expected MW is 54 kDa)
Figure 1: Western blot analysis using MMP3 mAb against human MMP3 (AA: 189-441) recombinant protein. (Expected MW is 54 kDa)
Flow cytometric
Figure 2: Flow cytometric analysis of NIH/3T3 cells using MMP3 mouse mAb (green) and negative control (red).
Figure 2: Flow cytometric analysis of NIH/3T3 cells using MMP3 mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

References (references)
References (references)1. Int J Cancer. 2009 May 1;124(9):2172-8.
2. Cancer Epidemiol Biomarkers Prev. 2008 Dec;17(12):3551-7.