MMP3 Primary Antibody
Item Information
Catalog #
Size
Price
Description
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Product Overview
Entrez GenelD
4314
Aliases
SL-1; STMY; STR1; CHDS6; MMP-3; STMY1
Clone#
4F10
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human MMP3 expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1. Int J Cancer. 2009 May 1;124(9):2172-8.
2. Cancer Epidemiol Biomarkers Prev. 2008 Dec;17(12):3551-7.
2. Cancer Epidemiol Biomarkers Prev. 2008 Dec;17(12):3551-7.
Product Image
Western Blot
Figure 1: Western blot analysis using MMP3 mAb against human MMP3 (AA: 189-441) recombinant protein. (Expected MW is 54 kDa)
Flow cytometric
Figure 2: Flow cytometric analysis of NIH/3T3 cells using MMP3 mouse mAb (green) and negative control (red).
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
For Research Use Only. Not for use in diagnostic procedures.