MEF2C Primary Antibody
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human MEF2C (AA: 1-125) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|Species Reactivity||Human, Mouse|
|IHC_P(Immunohistochemistry)||1/200 - 1/1000|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using MEF2C mAb against human MEF2C recombinant protein. (Expected MW is 40 kDa)
Figure 2: Western blot analysis using MEF2C mAb against HEK293 (1) and MEF2C (AA: 1-125)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3: Western blot analysis using MEF2C mouse mAb against NIH3T3 (1) and 3T3-L1 (2) cell lysate.
Figure 4: Flow cytometric analysis of HeLa cells using MEF2C mouse mAb (green) and negative control (purple).
Figure 5: Immunohistochemical analysis of paraffin-embedded colon cancer tissues using MEF2C mouse mAb with DAB staining.
Figure 6: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using MEF2C mouse mAb with DAB staining.
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
|Description||This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. |
|References (references)||1.PLoS One. 2011;6(11):e27165. |
2.J Biol Chem. 2011 Aug 26;286(34):30071-86.