MATN1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesMAT; SAMS; MATA1; SAMS1; MAT1A
ProductOrderM
Clone#5A8
Entrez GenelD4146
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human MATN1 expressed in E. Coli.
MW54kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
427-496
Catalog#: 30114
Inquire
Contact us to order
Images
Western Blot
Figure 1: Western blot analysis using MATN1 mAb against HEK293 (1) and MATN1(AA: 427-496)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 1: Western blot analysis using MATN1 mAb against HEK293 (1) and MATN1(AA: 427-496)-hIgGFc transfected HEK293 (2) cell lysate.
Immunofluorescence analysis
Figure 2: Immunofluorescence analysis of Hela cells using MATN1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Figure 2: Immunofluorescence analysis of Hela cells using MATN1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Product Overview
Description

This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.

References (references)
References (references)1. Biochem J. 1993 Jul 15;293 ( Pt 2):481-6.
2. Am J Hum Genet. 1997 Mar;60(3):540-6.
3. Am J Hum Genet. 2000 Feb;66(2):347-55.