MATK Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesCHK; CTK
ProductOrderM
Clone#9D7
Entrez GenelD4145
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human MATK expressed in E. Coli.
MW56kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
50-196
Catalog#: 20390
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Images
Western Blot
Figure 1: Western blot analysis using MATK mouse mAb against K562 cell lysate (1).
Figure 1: Western blot analysis using MATK mouse mAb against K562 cell lysate (1).
Flow cytometric
Figure 2: Flow cytometric analysis of K562 cells using MATK mouse mAb (green) and negative control (purple).
Figure 2: Flow cytometric analysis of K562 cells using MATK mouse mAb (green) and negative control (purple).
Product Overview
Description

MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.

References (references)
References (references)1. Int J Oncol. 2002 Jul;21(1):197-205.
2. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903.
3. Nat Genet. 2004 Jan;36(1):40-5.