MAPK7 Primary Antibody
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.
2. PLoS One. 2009;4(5):e5565.
![Figure 1: Western blot analysis using MAPK7 mAb against human MAPK7 (AA: 411-556) recombinant protein. (Expected MW is 41.8 kDa)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/30654rwb_1.jpg?v=1666703208)
![Figure 2: Western blot analysis using MAPK7 mAb against HEK293 (1) and MAPK7 (AA: 411-556)-hIgGFc transfected HEK293 (2) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/30654twb_1.jpg?v=1666703208)
![Figure 3: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using MAPK7 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/30654ihc-1_1.jpg?v=1666703208)
![Figure 4: Immunohistochemical analysis of paraffin-embedded colon cancer tissues using MAPK7 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/30654ihc-2_1.jpg?v=1666703209)
![Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/30654ea_1.jpg?v=1666703209)