MAPK11 Primary Antibody
Item Information
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Price
Description
Mitogen-activated protein kinase 11.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
Product Overview
Entrez GenelD
5600
Aliases
MAPK11
Clone#
4H6H6
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of MAPK11 (aa251-363) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Mol Cell Biol. 2005 Dec;25(23):10454-64.
2. Biol Reprod. 2005 Dec;73(6):1282-8. Epub 2005 Aug 24.
2. Biol Reprod. 2005 Dec;73(6):1282-8. Epub 2005 Aug 24.
Product Image
Western Blot
Figure 1: Western blot analysis using MAPK11 mouse mAb against truncated MAPK11 recombinant protein (1) and full-length MAPK11 (aa1-363)-pcDNA3.1 transfected CHO-K1 cell lysate (2).
For Research Use Only. Not for use in diagnostic procedures.