LRP1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesAPR; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R
ProductOrderL
Clone#3F12E2
Entrez GenelD4035
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human LRP1 (AA: 20-155) expressed in E. Coli.
MW50.5kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
IHC_P(Immunohistochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
20-155
Catalog#: 30851
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Images
Elisa
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western Blot
Figure 2:Western blot analysis using LRP1 mAb against human LRP1 (AA: 20-155) recombinant protein. (Expected MW is 40.8 kDa)
Figure 2:Western blot analysis using LRP1 mAb against human LRP1 (AA: 20-155) recombinant protein. (Expected MW is 40.8 kDa)
Western Blot
Figure 3:Western blot analysis using LRP1 mAb against HEK293 (1) and LRP1 (AA: 20-155)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3:Western blot analysis using LRP1 mAb against HEK293 (1) and LRP1 (AA: 20-155)-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemical analysis
Figure 5:Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using LRP1 mouse mAb with DAB staining.
Figure 5:Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using LRP1 mouse mAb with DAB staining.
Flow cytometric
Figure 6:Flow cytometric analysis of Jurkat cells using LRP1 mouse mAb (green) and negative control (red).
Figure 6:Flow cytometric analysis of Jurkat cells using LRP1 mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 6:Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using LRP1 mouse mAb with DAB staining.
Figure 6:Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using LRP1 mouse mAb with DAB staining.
Product Overview
DescriptionThe protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients.
References (references)
References (references)1.J Biol Chem. 2014 Feb 14;289(7):4135-44.
2.Aging (Albany NY). 2013 Nov;5(11):835-49.