LMO2 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesTTG2; RBTN2; RHOM2; RBTNL1
ProductOrderL
Clone#4D8
Entrez GenelD4005
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human LMO2 (AA: 1-158) expressed in E. Coli.
MW18.4kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISAPropose dilution 1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
full(1-158)
Catalog#: 30421
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Images
Western Blot
Figure 1: Western blot analysis using LMO2 mAb against human LMO2 recombinant protein. (Expected MW is 43.9 kDa)
Figure 1: Western blot analysis using LMO2 mAb against human LMO2 recombinant protein. (Expected MW is 43.9 kDa)
Western Blot
Figure 2: Western blot analysis using LMO2 mAb against HEK293 (1) and LMO2 (AA: 1-158)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using LMO2 mAb against HEK293 (1) and LMO2 (AA: 1-158)-hIgGFc transfected HEK293 (2) cell lysate.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
DescriptionLMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.

References (references)
References (references)1.FEBS J. 2011 Sep;278(17):3065-75.
2.Leuk Lymphoma. 2011 Jun;52(6):1146-9.