LILRB5 Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Overview
Entrez GenelD
10990
Aliases
LIR8; CD85C; LIR-8
Clone#
6D3C8
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human LILRB5 (AA: extra 24-164) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Sci Rep. 2016 Feb 24;6:21780.
2.Circ Cardiovasc Genet. 2014 Dec;7(6):880-6.
2.Circ Cardiovasc Genet. 2014 Dec;7(6):880-6.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using LILRB5 mAb against human LILRB5 (AA: extra 24-164) recombinant protein. (Expected MW is 41.5 kDa)
Western Blot
Figure 3:Western blot analysis using LILRB5 mAb against HEK293 (1) and LILRB5 (AA: extra 24-164)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of HL-60 cells using LILRB5 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.