LILRB2 Primary Antibody
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
![Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31475ea.jpg?v=1666703741)
![Figure 2:Western blot analysis using LILRB2 mAb against human LILRB2 (AA: 51-184) recombinant protein. (Expected MW is 41 kDa)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31475rwb.jpg?v=1666703741)
![Figure 3:Western blot analysis using LILRB2 mAb against HEK293 (1) and LILRB2 (AA: 51-184)-hIgGFc transfected HEK293 (2) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31475twb.jpg?v=1666703741)
![Figure 4:Western blot analysis using LILRB2 mouse mAb against MOLT4 (1) and K562 (2) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31475lwb.jpg?v=1666703741)
![Figure 5:Flow cytometric analysis of HL-60 cells using LILRB2 mouse mAb (green) and negative control (red).](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31475fcm.jpg?v=1666703741)