KLHL25 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesENC2; ENC-2; FLJ12587; FLJ45015; KLHL25
ProductOrderK
Clone#1B7
Entrez GenelD64410
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG2b
ImmunogenPurified recombinant fragment of human KLHL25 expressed in E. Coli.
MW65kDa
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Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
2-230
Catalog#: 30065
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Images
Western Blot
Figure 1: Western blot analysis using KLHL25 mAb against KLHL25(AA: 2-230)-hIgGFc transfected HEK293 cell.
Figure 1: Western blot analysis using KLHL25 mAb against KLHL25(AA: 2-230)-hIgGFc transfected HEK293 cell.
Product Overview
Description

KLHL25 (ectoderm-neural cortex protein 2, ENC2) is a cytoplasmic protein that contains six Kelch regions and a single BTB (POZ) domain. KLHL25 is highly homologus to another Kelch-like protein, ENC1, and it is believed to operate in a manner similar to other Kelch-domain containing proteins. Kelch-domain repeat containing proteins often act as modifiers of Actin fibers. Expressed early in embryogenesis, ENC1 helps to mediate neuronal process formation. It also appears to have a role in neural crest cell differentiation. KLHL25 likely functions as a substrate specific adapter for protein ubiquitinating complexes. KLHL25 is expressed in most tissues with highest expression in brain and liver.

References (references)
References (references)1. BMC Med Genet. 2007 Sep 19;8 Suppl 1:S13.
2. Genome Res. 2004 Oct;14(10B):2136-44.