KLHL25 Primary Antibody
Item Information
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Price
Description
KLHL25 (ectoderm-neural cortex protein 2, ENC2) is a cytoplasmic protein that contains six Kelch regions and a single BTB (POZ) domain. KLHL25 is highly homologus to another Kelch-like protein, ENC1, and it is believed to operate in a manner similar to other Kelch-domain containing proteins. Kelch-domain repeat containing proteins often act as modifiers of Actin fibers. Expressed early in embryogenesis, ENC1 helps to mediate neuronal process formation. It also appears to have a role in neural crest cell differentiation. KLHL25 likely functions as a substrate specific adapter for protein ubiquitinating complexes. KLHL25 is expressed in most tissues with highest expression in brain and liver.
Product Overview
Entrez GenelD
64410
Aliases
ENC2; ENC-2; FLJ12587; FLJ45015; KLHL25
Clone#
1B7
Host / Isotype
Mouse / IgG2b
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human KLHL25 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. BMC Med Genet. 2007 Sep 19;8 Suppl 1:S13.
2. Genome Res. 2004 Oct;14(10B):2136-44.
2. Genome Res. 2004 Oct;14(10B):2136-44.
Product Image
Western Blot
Figure 1: Western blot analysis using KLHL25 mAb against KLHL25(AA: 2-230)-hIgGFc transfected HEK293 cell.
For Research Use Only. Not for use in diagnostic procedures.