KLHL12 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesDKIR; C3IP1; FLJ27152; KLHL12
ProductOrderK
Clone#2G2
Entrez GenelD59349
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human KLHL12 expressed in E. Coli.
MW63kDa
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Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
205-466
Catalog#: 30058
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Images
Western Blot
Figure 1: Western blot analysis using KLHL12 mouse mAb against Hela (1) cell lysate.
Figure 1: Western blot analysis using KLHL12 mouse mAb against Hela (1) cell lysate.
Product Overview
Description

Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.

References (references)
References (references)1. Exp Cell Res. 2004 Oct 15;300(1):72-83.
2. Gene. 1994 Jan 28;138(1-2):171-4.