KIAA1967 Primary Antibody
|Aliases||DBC1; DBC-1; NET35; p30DBC; p30 DBC|
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Immunogen||Purified recombinant fragment of human KIAA1967 expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|IHC_P(Immunohistochemistry)||1/200 - 1/1000|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
Figure 1: Western blot analysis using KIAA1967 mouse mAb against HeLa (1) and HepG2 (2) cell lysate.
Figure 2: Flow cytometric analysis of HeLa cells using KIAA1967 mouse mAb (green) and negative control (purple).
Figure 3: Immunohistochemical analysis of paraffin-embedded colon cancer tissues using KIAA1967 mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using KIAA1967 mouse mAb with DAB staining.
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
|Description||DBC1 (deleted in breast cancer 1) is a novel transcriptional coactivator that has been suggested to be a critical regulator of tumorigenesis. It has been reported to be strongly related with unfavorable clinical outcome in several cancers, including breast and gastric cancer, and the protein is a key regulator of SIRT1 activity in vivo. |
|References (references)||1.J Biol Chem. 2012 Jul 6;287(28):23489-501. |
2.Histol Histopathol. 2012 Jan;27(1):49-58.