Ki67 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesKIA; Ki-67; MKI67
ProductOrderK
Clone#9C12B2
Entrez GenelD4288
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of Ki167 (aa3118-3256) expressed in E. Coli.
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
3118-3256
Catalog#: 20305
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Images
Western Blot
Figure 1: Western blot analysis using Ki67 mouse mAb against truncated Trx-Ki67 recombinant protein(1),truncated Ki67 (aa3118-3256)-His recombinant protein(2) and truncated Ki67 (aa3118-3256)-hIgGFc transfected CHO-K1 cell lysate(3).
Figure 1: Western blot analysis using Ki67 mouse mAb against truncated Trx-Ki67 recombinant protein(1),truncated Ki67 (aa3118-3256)-His recombinant protein(2) and truncated Ki67 (aa3118-3256)-hIgGFc transfected CHO-K1 cell lysate(3).
Product Overview
Description

Ki67: antigen identified by monoclonal antibody Ki-67. Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.

References (references)
References (references)1. Folia Histochem Cytobiol. 2007;45(4):357-66.
2. Tumori. 2008 May-Jun;94(3):389-97.