KDR Primary Antibody
Item Information
Catalog #
Size
Price
Description
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
Product Overview
Entrez GenelD
3791
Aliases
FLK1; CD309; VEGFR; VEGFR2
Clone#
1A9A3
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human KDR (AA: 1225-1356) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Autophagy. 2017 Sep 2;13(9):1528-1542.
2.Pathol Res Pract. 2015 Jul;211(7):539-43.
2.Pathol Res Pract. 2015 Jul;211(7):539-43.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using KDR mAb against human KDR (AA: 1225-1356) recombinant protein. (Expected MW is 40.2 kDa)
Western Blot
Figure 3:Western blot analysis using KDR mAb against HEK293 (1) and KDR (AA: 1225-1356)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of Hela cells using KDR mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.